Thorne Adrenal Cortex is an adrenal supplement used to treat a variety of conditions that involve cortisol levels. The most common condition users take adrenal cortex for is “adrenal fatigue.” In other words, a reduction in adrenal hormone production due to excessive stress caused by modern life.

Thorne Adrenal Cortex is a supplement that is, like all adrenal cortex supplements, made from the adrenal glands of animals such as cows or pigs. Proponents believe that by consuming extracts made from animals’ adrenal glands, human adrenal gland function can be regulated.

Adrenal cortex’s primary active ingredient is the hormone hydrocortisone. It was widely used in the early twentieth century to treat several ailments, but has since been replaced by other medicines. Today, proponents of adrenal cortex claim that hydrocortisone increases energy and memory, and provides natural stress relief.

It is worth noting that no reliable scientific research suggests adrenal cortex can accomplish these benefits. It is not clear if humans can absorb adrenal cortex extract. And, there is no scientific basis for the diagnosis of “adrenal fatigue.” However, thousands of people report an improvement in their lives after taking adrenal cortex. Many users say that adrenal cortex helped ease their maladies’ symptoms, such as chronic candida.

That being said, Thorne Adrenal Cortex includes only bovine adrenal cortex. The product comes in capsule form and is taken orally one to three times daily based on a recommendation from a healthcare professional.

Features and Benefits

Thorne Research Adrenal Cortex is highly rated in online marketplaces. There are also some aspects that set it apart from other supplements.


While the active ingredient is bovine adrenal cortex, there are other ingredients in the capsule to ensure that it retains its shape and can be swallowed and digested easier. These ingredients include…

  • Microcrystalline Cellulose
  • Hypromellose (derived from cellulose) capsule
  • Silicon Dioxide

All the ingredients are hypoallergenic, which means there are no substances in the product that have been shown to cause allergic reactions. There are also no known adverse interactions or contraindications. That means the product has not caused any severe side effects due to interactions with other medications.

Increased Hormone Production

Human adrenal glands are responsible for producing hormones called corticosteroids. Corticosteroids regulate many bodily functions including the immune system, blood pressure, sex drive and more. Reduced levels of corticosteroids may result in diminished capacity in these areas. Thorne Adrenal Cortex aims to boost adrenal gland function, thereby increasing corticosteroid levels.

The stimulation of the adrenal glands “causes a release of cortisol, epinephrine, and norepinephrine, facilitating physiologic changes in most tissues of the body.” These physiological changes can consist of increased blood pressure, raised blood sugar and constricted blood vessels of the digestive tract which aids in digestion.

Lower Stress Levels

Users of Thorne Adrenal Cortex report both lowered stress and increased stress tolerance. This lowering of stress is attributed to reductions in the causes of stress. Users take cortex extracts to reduce fatigue, fight depression, increase energy, and raise blood pressure and blood sugar levels. Many users also say that it regulates mood and eases emotional distress. All of these benefits contribute to decreased levels of stress and a better ability to cope.

Boosted Immune System

The adrenal glands, as stated above, help to regulate the body’s immune system. By improving adrenal gland function, one can strengthen their immune system. They can also ease the symptoms of autoimmune disorders. Thorne cortex claims to support immune system health in this way, thereby reducing the probability of falling ill.

What Makes It Unique?

Thorne Research Adrenal Cortex supplements are made from only cortex tissues of the bovine. Other supplements use the entire gland in production of the product. They are referred to by some as “glandulars.” Some users have issues with glandulars. Therefore, it’s recommended to take only cortex tissue based supplements. Thorne Adrenal Cortex is one such supplement, so users who are sensitive to glandulars will find this product to be a viable alternative. A healthcare professional can advise you on which type of adrenal cortex supplement is best for you.


In comparison to other adrenal cortex supplements, adrenal cortex from Thorne is a bit on the expensive side. But, it is by no means excessively overpriced. As it is a supplement, the price can fluctuate wildly depending on the vendor. A consumer can expect to pay around $12-$20 for a bottle of 60 capsules. It is possible to find different brands at lower cost or increased capsule count, but the difference is small.

What Could Be Better?

There are a few downsides and drawbacks to Thorne Adrenal Cortex as reported by consumers. There are also some misleading claims on the bottle itself.

“Vegetarian Capsules”: This claim refers to the capsules themselves, and not the active ingredient found in the capsules. This product contains animal tissues.

Lowered Strength: Some users report that the level of adrenal cortex tissue is not enough for their needs. Some state that they need a stronger product to notice a change. A portion of users reported no change in their bodies.

Rare Side Effects: It is possible to react negatively to adrenal cortex supplements; Thorne adrenal cortex side effects include upset stomach or vomiting, but are generally mild.


Thorne Adrenal Cortex is a product with decent ratings on online supplement marketplaces. Many buyers report higher energy levels and reduced stress from using this product. It is slightly more expensive than other products of its kind, but the difference is rather small. Plus, it has the added benefit of having only cortex tissue in it. Since some users do not – or cannot use glandular adrenal products that include all parts of an animal’s adrenal gland – this can be a significant benefit. No severe side effects have been reported, but since it is a supplement, it is not monitored by the FDA.

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